Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Methionine Metabolic Pathway
- Molecular classification
- Metabolic Pathway
01
Overview
The methionine metabolic pathway is a central biochemical network responsible for the synthesis, utilization, and recycling of the essential amino acid methionine. This pathway is crucial for protein synthesis, methyl group transfers (methylation reactions), antioxidant defense, and the biosynthesis of other sulfur-containing compounds such as cysteine and polyamines. Disruptions or deficiencies in this pathway are linked with several disorders including homocystinuria, hyperhomocysteinemia and megaloblastic anemia.
- Other names
- Methionine CycleActivated Methyl CycleTranssulfuration PathwayMethionine Salvage PathwayMTA Cycle
02
Mechanism of action
N/A - This is a pathway, not a single target.
03
Biological functions
Protein synthesis initiationUniversal methyl donor productionAntioxidant precursor biosynthesisCysteine biosynthesisPolyamines biosynthesis
04
Disease associations
HomocystinuriaHyperhomocysteinemiaCardiovascular diseaseMegaloblastic anemiaNeurotransmitter imbalanceEpigenetic dysregulationRedox homeostasis imbalance
05
Safety considerations
Elevated homocysteine levels (homocysteinemia)Vascular riskNeurotoxicityImpaired methylation reactions
06
Interacting drugs
Vitamin B12
2 more in the full profile.
07
Biomarkers
Methionine levelsHomocysteine levelsSAM levelsSAH levelsCysteine levels
Beyond the preview
Go deeper on Methionine Metabolic Pathway.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Methionine Metabolic Pathway.