Target intelligence / Profile preview

Methionyl aminopeptidase 2 pseudogene (METAP2P)

Target
METAP2P
Molecular classification
Other (Pseudogene)
01

Overview

The Methionyl aminopeptidase 2 pseudogene (ENSG00000273444) is a DNA sequence in the human genome that closely resembles the gene coding for *methionyl aminopeptidase 2* (METAP2), but is classified as a **pseudogene**[5][2]. Pseudogenes like ENSG00000273444 arise from gene duplication or retrotransposition events, and while they have sequence similarity to functional genes, they lack the ability to produce functional protein products owing to disabling mutations or lack of regulatory elements[2][5]. Pseudogenes can sometimes be transcribed or contribute to cellular regulation (such as acting as a source of non-coding RNAs or influencing gene expression), but their function is usually limited and they are not considered valid drug targets or associated directly with disease mechanisms[2][5][8].

Other names
Methionyl aminopeptidase 2 pseudogeneMETAP2PMethionyl aminopeptidase 2 (METAP2) pseudogene
02

Biological functions

May be transcribed at low levels, but does not produce a functional proteinPossible roles in gene regulation (e.g., noncoding RNA functions, competitive endogenous RNA)Generally considered non-functional
03

Disease associations

Other (Pseudogenes are not usually implicated in disease as direct causes, but can affect gene regulation. Functional METAP2 (not the pseudogene) is linked to cancer and obesity, but this does not apply to the pseudogene itself)

Beyond the preview

Go deeper on Methionyl aminopeptidase 2 pseudogene (METAP2P).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Full profile access

Explore the programs pursuing this target and their development progress.

  • Drug candidates
  • Developers
  • Development stage

Clinical trials

Full profile access

Follow the clinical studies evaluating therapies directed at this target.

  • Trial design
  • Status
  • Readouts

Competitive landscape

Full profile access

Compare approaches across drug candidates, modalities, and indications.

  • Programs
  • Modalities
  • Indications

Literature & evidence

Full profile access

Investigate the research and source evidence behind target biology and development.

  • Publications
  • Sources
  • Analysis

Patents

Full profile access

Explore patent activity around therapies and technologies addressing this target.

  • Patents
  • Assignees
  • Technologies

Research & analysis

Full profile access

Connect target biology, drug development, and emerging evidence in your research.

  • Biology
  • Development news
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Methionyl aminopeptidase 2 pseudogene (METAP2P).

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call