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Methylenetetrahydrofolate dehydrogenase 2, methenyltetrahydrofolate cyclohydrolase pseudogene 1 (MTHFD2P1)
- Target
- MTHFD2P1
- Molecular classification
- Other (Pseudogene)
01
Overview
MTHFD2P1 is a pseudogene of the methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) gene. Unlike the functional MTHFD2 enzyme, which is a mitochondrial enzyme involved in folate-mediated one-carbon metabolism and is a notable therapeutic target in oncology, MTHFD2P1 does not encode an active protein[1][2][3]. Pseudogenes like MTHFD2P1 may be remnants of evolutionary duplication events and, unless shown otherwise, are not considered functional targets in pharmacology or biomedical research. If your intention is to research a metabolic enzyme or therapeutic target, focus should be on MTHFD2, not MTHFD2P1.
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