Methylenetetrahydrofolate dehydrogenase 2, methenyltetrahydrofolate cyclohydrolase pseudogene 2 (MTHFD2P2)

MTHFD2P2 is a pseudogene related to the methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) gene family. Pseudogenes are genomic DNA sequences similar to normal genes but are nonfunctional; they arise from gene duplication or retrotransposition events. Unlike their functional counterparts, pseudogenes like MTHFD2P2 do not encode active proteins and are not considered biological drug targets, enzymes, or receptors. Thus, MTHFD2P2 has no known enzymatic activity, disease associations, or roles as a target for drugs or biomarkers. Any references to "methylenetetrahydrofolate dehydrogenase activity," known for MTHFD2, do not apply to MTHFD2P2. MTHFD2P2 is a pseudogene and not an active enzyme, receptor, or molecular target. It does not perform biological functions, is not implicated in disease, and has no relevance as a therapeutic target. Any scientific or pharmaceutical interest in folate metabolism or cancer generally refers to the actual MTHFD2 enzyme (not the pseudogene MTHFD2P2)[2][4].

Other names

MTHFD2P2