Target intelligence / Profile preview

Methylenetetrahydrofolate dehydrogenase 2, methenyltetrahydrofolate cyclohydrolase pseudogene 3 (MTHFD2P3)

Target
MTHFD2P3
Molecular classification
Other (Pseudogene)
01

Overview

MTHFD2P3 is officially annotated as a pseudogene, which means it is a segment of DNA similar to the functional methylenetetrahydrofolate dehydrogenase 2 gene but is typically considered non-coding and non-functional. Pseudogenes generally do not produce active protein products and lack direct biological or clinical relevance. Their presence may be noted in genomic studies, but MTHFD2P3 itself is not an enzyme, receptor, or transporter, nor is it established as a therapeutic target. Information on MTHFD2P3 is limited, and it should not be confused with MTHFD2, which is an active mitochondrial enzyme involved in folate metabolism and cell proliferation, and has emerging implications in cancer biology[2][4].

Other names
MTHFD2P3Methylenetetrahydrofolate dehydrogenase (NAD+) 2 pseudogene 3Methenyltetrahydrofolate cyclohydrolase pseudogene 3
02

Mechanism of action

None known

03

Biological functions

Other (No known direct biological function; presumed non-coding)
04

Disease associations

Other (No established disease associations)

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