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Target intelligence / Profile preview
MHC class I polypeptide-related sequence C (pseudogene) (MICC)
- Target
- MICC
- Molecular classification
- Other (Pseudogene)
01
Overview
MHC class I polypeptide-related sequence C (MICC), also known as PERB11.3, is a human pseudogene; it does not encode a functional protein. While other MHC class I polypeptide-related sequences (like MICA and MICB) produce cell-surface proteins that can act as ligands for immune receptors (notably NKG2D), MICC itself has no known protein product, function, or role as a receptor[1][3][5][9]. Therefore, it should not be considered a therapeutic target or biomarker.
- Other names
- PERB11.3MICC (abbreviation)
02
Mechanism of action
None applicable (no functional protein encoded).
03
Biological functions
None identified for the MICC pseudogene (does not produce a functional protein)
04
Disease associations
None. As a pseudogene, MICC is not directly implicated in disease processes.
05
Safety considerations
None specific to MICC as it does not produce an active molecule.
06
Interacting drugs
None described. No drugs are known to target or interact with this pseudogene.
07
Biomarkers
None described for MICC.
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