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MHC class I polypeptide-related sequence F pseudogene
- Molecular classification
- Pseudogene, Non-coding sequence
01
Overview
MHC class I polypeptide-related sequence F pseudogene (MICF) is a non-coding segment in the human genome classified as a pseudogene within the MHC class I gene family[7][4]. It does not produce a functional protein product and differs from functional MHC class I genes (such as MICA and MICB) that are implicated in immune response, antigen presentation, and as ligands for various T and NK cell receptors[1][4][7]. As a pseudogene, MICF has no role as a receptor, enzyme, or signaling target, and there is no evidence for involvement in disease or therapeutic modulation. This entry is considered not a true therapeutic target due to its classification as a pseudogene, and most databases do not provide functional or disease-related data for it[7][1][4].
- Other names
- MICFMHC class I polypeptide-related sequence F
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