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MIA2 antisense RNA 1 (MIA2-AS1)

Target: MIA2-AS1
Molecular classification: Long non-coding RNA, Antisense RNA

Overview

MIA2 antisense RNA 1 (MIA2-AS1) is a long non-coding RNA gene transcribed antisense to the MIA2 gene locus. It belongs to the lncRNA molecular class and is not a protein-coding gene, nor is it a classical receptor, enzyme, or transporter. MIA2-AS1 has been identified in gene-disease databases as associated with rheumatoid arthritis but has not been established as a direct therapeutic target. Its function is presumed to involve regulatory roles typical of lncRNAs, possibly in immune processes, but clinical targeting or biomarker use is unestablished[3].

Other names: MIA2-AS1

Mechanism of action

Not applicable; no drugs are known to target this molecule.

Biological functions

Gene regulation (potential regulatory roles through antisense mechanisms as with other lncRNAs)Potential modulation of immune processes

Disease associations

Rheumatoid arthritis (associated via gene-disease databases)The roles in other diseases such as cancer are proposed for the MIA gene family but not directly supported for MIA2-AS1

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