MICOS10 pseudogene 4 (MICOS10P4)

MICOS10 pseudogene 4 (MICOS10P4) is classified as a pseudogene that shares homology with the protein-coding MICOS10 gene, which is a component of the mitochondrial contact site and cristae organizing system (MICOS) complex[5]. Unlike its parent gene MICOS10, which encodes a subunit of the MICOS complex and is essential for mitochondrial cristae morphology and inner membrane architecture [3][1], MICOS10P4 does not produce a functional protein and has no proven role in health or disease. It is not considered a therapeutic target, nor is it known to interact with drugs or serve as a biomarker. Key point: MICOS10P4 is a nonfunctional genomic element (pseudogene) and should not be confused with MICOS10, which is an active protein-coding gene involved in mitochondrial structure and linked to certain mitochondrial diseases [1][3][5].