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Microbial Biofilm Matrix (N/A)
- Target
- N/A
- Molecular classification
- Extracellular matrix, Polysaccharide, Protein, Extracellular DNA, Lipid, Biopolymer
01
Overview
The microbial biofilm matrix is a complex, self-produced extracellular structure that encases microbial cells within a biofilm. It serves as both the scaffold and protective barrier for the community of microorganisms, facilitating adhesion to surfaces, cohesion among cells, nutrient cycling, and defense against environmental threats such as antibiotics and host immune responses. The matrix is primarily composed of water, polysaccharides, proteins, extracellular DNA (eDNA), lipids, and other biopolymers. Its composition and architecture vary widely depending on microbial species, environmental conditions, and stage of biofilm development.
- Other names
- Extracellular polymeric substance (EPS) matrixBiofilm matrix
02
Mechanism of action
Limiting penetration of antimicrobial agents; providing a protected environment for microbes.
03
Biological functions
AdhesionCohesionNutrient cyclingProtection from environmental stressorsHorizontal gene transferMetabolic support
04
Disease associations
InfectionAntibiotic resistance
05
Safety considerations
Contribution to antibiotic resistanceDifficulty in eradicating biofilms in chronic infections
06
Interacting drugs
Antibiotics
2 more in the full profile.
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