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Target intelligence / Profile preview
Microbial Cytosolic Enzyme (MCE)
- Target
- MCE
- Molecular classification
- Enzyme
01
Overview
Microbial cytosolic enzymes are protein biomolecules found within the cytosol of microbial cells, such as bacteria. These enzymes act as biocatalysts, regulating and accelerating various metabolic reactions essential for cell survival, growth, and adaptation. They are crucial for maintaining cellular homeostasis, supporting rapid growth under favorable conditions, and adapting to environmental changes through regulation of metabolic fluxes. Many antibiotics target unique bacterial enzymatic pathways not present in humans, making them attractive drug targets due to their specificity.
- Other names
- Bacterial Cytosolic EnzymeMicrobial Intracellular EnzymeCytoplasmic Enzyme (Microbial)Enzymes of Microbial Cytosol
02
Mechanism of action
Enzyme Inhibition
03
Biological functions
Metabolic CatalysisBiosynthesisEnergy ProductionEnvironmental AdaptationRegulation of metabolic fluxesCatalysis of biochemical reactions
04
Disease associations
InfectionAntibiotic Resistance
05
Safety considerations
Off-target effects on human enzymesDevelopment of resistancePotential for disruption of microbiome
06
Interacting drugs
Lysozyme
3 more in the full profile.
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