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Target intelligence / Profile preview
Microorganism Adhesion Protein (Adhesin)
- Target
- Adhesin
- Molecular classification
- Protein, Pili/Fimbrial, MSCRAMMs, Bap/LapA family, Polysaccharide adhesins
01
Overview
Microorganism adhesion proteins, or adhesins, are surface-exposed proteins that enable microorganisms to attach to host tissues, abiotic surfaces, or other cells. This adhesion is critical for colonization, infection initiation, biofilm formation, and pathogenesis. They are structurally diverse and facilitate specific interactions with host receptors, playing essential roles in both health-associated and disease-related microbial processes.
- Other names
- Adhesion proteinBacterial adhesinFungal adhesinSurface adhesion protein
02
Mechanism of action
Inhibition of adhesion to host cells or surfaces; disruption of biofilm formation
03
Biological functions
Cell adhesionHost cell bindingBiofilm formationColonizationVirulence
04
Disease associations
InfectionBiofilm-associated infectionsPathogenesisAntimicrobial resistance
05
Safety considerations
Potential for off-target effectsDevelopment of resistanceImmune response to adhesin-based therapies
06
Interacting drugs
Anti-adhesion drugs
2 more in the full profile.
07
Biomarkers
Adhesin expression levelsAntibody titers against adhesins
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