MicroRNA 1193 (miR-1193)

MicroRNA 1193 (miR-1193) is a small, non-coding RNA molecule belonging to the microRNA family, functioning as a post-transcriptional regulator of gene expression[5][6]. It binds to complementary sequences in the 3' untranslated regions of target messenger RNAs, resulting in reduced protein output either via mRNA degradation or translational repression[3]. miR-1193 has demonstrated biological roles in suppressing fibroblast proliferation, inducing apoptosis in inflammatory contexts such as rheumatoid arthritis, and acting as a tumor suppressor in leukemia cell models[2]. Its gene targets include proteins linked to cell cycle control, neural development, and apoptosis. Although not currently the direct target of any approved therapeutic drugs, its expression levels may serve as biomarkers for disease progression and response, with ongoing research into nucleic-acid based therapeutics. Safety considerations center on the risk of unintended gene regulation in clinical settings.

Other names

hsa-mir-1193MIR1193miR-1193

Directly targets mRNA transcripts via partial or complete base pairing, leading to mRNA degradation or translation inhibition\nModulates cellular pathways by repressing specific genes (e.g., USP15, PLPPR5, GSG1L)