MicroRNA 1226 (miR-1226)

MicroRNA 1226 (miR-1226) is a small, non-coding RNA of the microRNA family involved in post-transcriptional regulation of gene expression by binding to target mRNA, leading to mRNA destabilization or translational repression[3]. It has been implicated in the regulation of cell proliferation and apoptosis by targeting key proteins such as TRAF3 in osteosarcoma, promoting tumor cell proliferation and potentially affecting overall survival in patients with cancer[1]. Its expression and dysregulation have been associated with several diseases, including cancer, periodontitis, and inflammatory bowel disease[1][3]. As a regulatory RNA and not a proteinaceous receptor, transporter, or enzyme, miR-1226 is not considered a classic therapeutic target but may serve as a potential biomarker or a candidate for oligonucleotide drug development in the context of gene regulation[3][1].

Other names

hsa-mir-1226MIR1226MIRN1226mir-1226microRNA-1226-3p