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Target intelligence / Profile preview
MicroRNA 1302-2 (MIR1302-2)
- Target
- MIR1302-2
- Molecular classification
- Other (microRNA)
01
Overview
MicroRNA 1302-2 (MIR1302-2) is a non-coding RNA of the microRNA (miRNA) class, derived from the MER53 DNA transposable element. Like other microRNAs, MIR1302-2 is processed from primary transcripts to produce a mature, ~22 nucleotide RNA that associates with the RISC complex to regulate gene expression post-transcriptionally. The mature miRNA typically binds imperfectly to target mRNAs, inhibiting translation or promoting mRNA degradation. The miR-1302 family, including MIR1302-2, is notable for its evolutionary derivation from MER53 elements and its presence in multiple genomic locations as a result of segmental duplications. While predicted to regulate genes involved in transportation, localization, and developmental processes, the exact biological functions and clinical significance of MIR1302-2 remain unknown[1][2]. There is currently no evidence supporting MIR1302-2 as a therapeutic target, nor are there known drugs, biomarkers, or clear disease associations for this microRNA family member.
- Other names
- hsa-mir-1302-2MIRN1302-2MIR1302-2
02
Biological functions
Regulation of gene expressionModulation of mRNA stability and translationPotential role in transportation, localization, and system developmentPositive regulation of cellular processesPredicted involvement in binding and transcription regulation
03
Disease associations
Unknown (no direct disease associations or therapeutic targeting role established)
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