MicroRNA 1302-6 (MIR1302-6)

MicroRNA 1302-6 (MIR1302-6) is a member of the miR-1302 family, a group of placental-specific microRNAs derived from MER53 DNA transposable elements[1][2]. MicroRNAs (miRNAs) such as MIR1302-6 are short (20–24 nucleotide) non-coding RNAs that regulate gene expression post-transcriptionally by interfering with the stability and translation of mRNAs. MIR1302-6 is processed from a stem-loop precursor by Drosha and Dicer, ultimately joining the RNA-induced silencing complex (RISC), which targets mRNAs for translational inhibition or degradation through sequence complementarity. The miR-1302 family, including MIR1302-6, is involved in the regulation of genes overrepresented in processes such as cellular localization, transportation, system development, and transcriptional regulation, but specific functional or disease associations for MIR1302-6 have not been well established. Currently, there is no evidence to classify MIR1302-6 as a recognized therapeutic target, nor are there known drugs, mechanisms of action, biomarkers, or notable safety concerns directly associated with it[1][2].

Other names

hsa-mir-1302-6MIRN1302-6