MicroRNA 1324 (miR-1324)

MicroRNA 1324 is a member of the microRNA class of short (20–24 nucleotide) non-coding RNAs, which regulate gene expression in multicellular eukaryotes at the post-transcriptional level[1][6]. MIR1324 is processed from a precursor transcript through the typical Drosha/Dicer pathway. The mature miR-1324 is incorporated into the RNA-induced silencing complex (RISC), enabling recognition of target mRNAs via imperfect base pairing, most commonly resulting in translational inhibition or mRNA destabilization[1][6]. In the context of human disease, MIR1324 has been reported to inhibit cell proliferation and invasiveness in gastric cancer by targeting MECP2[1]. It is also associated with Hirschsprung Disease 1[1]. While microRNAs are increasingly investigated as therapeutic and diagnostic targets, MIR1324 itself does not have recognized direct drug interactions, validated biomarkers, or noted safety concerns. The broader family plays important regulatory roles in cell differentiation, proliferation, apoptosis, and disease biology[5][6].

Other names

hsa-mir-1324MIRN1324MIR1324GC00U923171

Not applicable (no direct drugs targeting MIR1324; miRNA-targeting therapies generally seek to modulate miRNA activity by mimic or inhibitor molecules, affecting gene silencing)