MicroRNA-190b (miR-190b)

MicroRNA-190b (miR-190b) is a small, non-coding RNA molecule that regulates gene expression post-transcriptionally by binding to target messenger RNAs, leading to their degradation or translational repression[1][3]. It has been identified as a tumor-suppressive microRNA in non-small cell lung cancer—where it is often down-regulated and associated with poor prognosis—and is notably overexpressed in estrogen receptor-positive (ER+) breast cancers, where high levels correlate with more favorable outcomes[1][3]. miR-190b targets genes involved in DNA repair and cell proliferation, such as HUS1 in lung cancer and RFWD3 in breast cancer, highlighting its role in cancer biology and potential as a biomarker for diagnosis and prognosis[1][3].

Other names

hsa-miR-190bMIR190Bhsa-mir-190bMIRN190Bmir-190b