Target intelligence / Profile preview

MicroRNA 2113 (MIR2113)

Target: MIR2113
Molecular classification: MicroRNA (miRNA), Non-coding RNA, Regulatory RNA

Overview

MicroRNA 2113 (MIR2113) is a small, non-coding RNA molecule that functions in the post-transcriptional regulation of gene expression by binding to complementary sequences on target mRNAs, leading to their degradation or inhibition of translation[5]. Like other human microRNAs, MIR2113 is transcribed as a stem-loop precursor and processed into a mature microRNA, which is incorporated into the RNA-induced silencing complex (RISC). Changes or variants in the MIR2113 sequence have been reported in some studies to associate with neuropsychiatric diseases such as bipolar disorder, but its specific biological functions and validated mRNA targets remain to be clearly defined[3][5]. There is no current evidence supporting direct pharmacological targeting or clinical biomarker use.

Other names: hsa-mir-2113MIR2113microRNA 2113

Mechanism of action

Not applicable, as there are no known drugs targeting microRNA 2113.

Biological functions

Post-transcriptional gene regulation via RNA silencing mechanisms[5][3]Regulation of gene expression in various tissues (function in specific pathways remains under investigation)

Disease associations

Some studies associate genetic variation within MIR2113 with neuropsychiatric disorders such as bipolar disorder[3].Its broader disease association profile is not well established in available literature, and unlike some miRNAs (such as MIR21 or MIR34a), there is no strong evidence for a direct role in cancer, cardiovascular disease, or other common pathological processes as of current evidence[3].

Safety considerations

None reported or known, as MIR2113 is not currently a direct therapeutic target.

Interacting drugs

None known. No drugs are known to directly target MIR2113 as of current literature, and no drug–microRNA interaction is established for this specific microRNA[3][5].

Biomarkers

None established for patient selection or efficacy monitoring, though variants in the MIR2113 locus have been studied as possible genetic markers in neuropsychiatric research[3].

Beyond the preview

Go deeper on MicroRNA 2113 (MIR2113).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on MicroRNA 2113 (MIR2113).

Explore the full profile