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Target intelligence / Profile preview
MicroRNA 23b (miR-23b)
- Target
- miR-23b
- Molecular classification
- Non-coding RNA, MicroRNA
01
Overview
MicroRNA 23b (miR-23b) is a small, non-coding RNA molecule that plays a crucial role in the post-transcriptional regulation of gene expression. It functions primarily by binding to complementary sequences in target messenger RNAs (mRNAs), leading to their degradation or translational repression. miR-23b regulates several key cellular processes, including cell proliferation, differentiation, and apoptosis. It has been implicated in cancer, autoimmune diseases, and neurological disorders. Its expression levels are often altered in various diseases and are associated with clinical outcomes, making it a potential biomarker and therapeutic target.
- Other names
- MIR23Bhsa-miR-23b
02
Mechanism of action
Binds to complementary sequences in target mRNAs, leading to their degradation or translational repression.
03
Biological functions
Post-transcriptional gene silencingRegulation of proliferationRegulation of apoptosisRegulation of differentiationCell cycle controlInflammatory response
04
Disease associations
CancerAutoimmune disordersNeurodegenerative diseases
05
Safety considerations
Acts as both tumor suppressor and oncogene depending on context.
06
Biomarkers
Dysregulation in plasma/serum as a potential biomarker for diagnosis or prognosis across multiple malignancies
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