Target intelligence / Profile preview

MicroRNA 2467 (MIR2467)

Target
MIR2467
Molecular classification
microRNA, non-coding RNA
01

Overview

MicroRNA 2467 (MIR2467) is a short (20–24 nucleotides), non-coding RNA molecule predicted in humans and classified within the microRNA family. MicroRNAs are transcribed by RNA Polymerase II and processed through Drosha and Dicer enzymes, resulting in a mature miRNA incorporated into the RNA-induced silencing complex (RISC). They function to suppress or sometimes activate gene expression post-transcriptionally, most commonly through imperfect base-pairing with their target mRNAs, resulting in translational inhibition or mRNA destabilization. While microRNAs broadly play roles in cell cycle regulation, development, apoptosis, and immune modulation, the specific biological targets and functions for MIR2467 have not been experimentally validated as of current literature and database records. MIR2467 is officially recognized by genetic databases (HGNC: 41881, NCBI Gene: 100616360, Ensembl: ENSG00000264292, miRBase: hsa-mir-2467). There is no evidence it is used as a therapeutic target or biomarker, nor are any drugs known to interact with it. Its function is extrapolated from general miRNA activity, as experimental data on MIR2467 itself is lacking. No specific biological, disease, or therapeutic roles have been established for MIR2467. Information is general to the miRNA family and not unique to this molecule.

Other names
hsa-mir-2467mir-2467microRNA 2467
02

Mechanism of action

none established for drugs targeting MIR2467

03

Biological functions

post-transcriptional regulation of gene expressionmodulation of mRNA stability and translation
04

Disease associations

possibly associated with Brachydactyly (based on gene-level association)other disease links unknown or uncharacterized specifically for MIR2467

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