MicroRNA 302f (miR-302f)

MicroRNA 302f (miR-302f) is a member of the miR-302 family, a group of small (~19–25 nucleotides), non-coding RNAs that act as post-transcriptional regulators of gene expression[3]. Like other microRNAs, miR-302f regulates its target mRNAs primarily by binding to complementary sequences in the 3' untranslated region, leading to mRNA degradation or translational repression[3]. The miR-302 family is highly expressed in embryonic stem cells and has a key role in the maintenance of stem cell pluripotency, in the regulation of cell cycle progression, and in pathways related to cell proliferation and apoptosis[3][1]. Dysregulation of miR-302 family members, although most studies focus on other paralogs, has been associated with cancer development, where they can function as tumor suppressors or oncogenes through their gene regulatory networks[3][1]. miR-302f is encoded by a gene in the human genome (symbol: MIR302F) and is also referenced as hsa-miR-302f. Notes and limitations: - No evidence was found that miR-302f (MIR302F) is a currently validated or direct therapeutic target (such as a druggable receptor or enzyme)[3][1]. - Most disease associations for the miR-302 family focus on other family members; data specific to miR-302f remains limited. - No drugs are known to directly target miR-302f as of current knowledge. - Like other microRNAs, miR-302f may serve as a potential biomarker or therapeutic tool in the future, but there is insufficient specific evidence to list validated biomarkers or drugs at this time.

Other names

hsa-miR-302fMIRN302FMIR302Fhsa-mir-302f