Target intelligence / Profile preview

MicroRNA 3118-3 (MIR3118-3)

Target
MIR3118-3
Molecular classification
Non-coding RNA, microRNA (miRNA) family
01

Overview

MicroRNA 3118-3 is a short, non-coding RNA gene in humans from the class of microRNAs (miRNAs), which are approximately 20–24 nucleotides in length and regulate gene expression post-transcriptionally by promoting mRNA degradation or inhibiting translation. MIR3118-3 is transcribed as part of a longer primary transcript, processed by RNase III enzymes (Drosha and Dicer) to yield the mature miRNA[1][3][4][5]. While the general function of miRNAs involves regulation of development, differentiation, cell cycle, and apoptosis, there are currently no experimentally validated or disease-specific roles described for MIR3118-3 itself in public databases or the literature. As such, it is best classified as a non-coding RNA with post-transcriptional regulatory potential, but not as a receptor, enzyme, or typical drug target[1][4].

Other names
hsa-mir-3118-3MIR3118-3ENSG00000277243 (Ensembl)NCBI Gene: 100422844HGNC: 38274
02

Mechanism of action

Not applicable for MIR3118-3 specifically; microRNAs generally regulate target mRNA via gene silencing or translational repression.

03

Biological functions

Post-transcriptional regulation of gene expressionmRNA destabilization and translational inhibitionPotential roles in developmental processes and cell state regulation (by analogy to other miRNAs)
04

Disease associations

Cancer (broad class, but not specific to MIR3118-3)Developmental disorders, cell differentiation, apoptosis, immune response

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