Target intelligence / Profile preview

MicroRNA 3144 (miR-3144)

Target
miR-3144
Molecular classification
Non-coding RNA, MicroRNA (miRNA) family, Other
01

Overview

MicroRNA 3144 is a short, non-coding RNA that modulates gene expression post-transcriptionally. It is involved in cell regulation pathways and, through RNA editing, is implicated in liver cancer cell proliferation and differentiation. No targeted therapies currently exist; its role as a biomarker and therapeutic target is under preclinical investigation.

Other names
MIR3144miR-3144hsa-mir-3144mir-3144microRNA 3144HGNC:38331NCBI Gene: 100422951Ensembl: ENSG00000265725miRBase: hsa-mir-3144
02

Biological functions

Post-transcriptional gene regulationFine-tuning gene expressionCell proliferationCell differentiationOther
03

Disease associations

Cancer
04

Safety considerations

Therapeutic challenges in miRNA targetingoff-target effects due to editinggeneral delivery and specificity issues with miRNA-based therapies
05

Biomarkers

Editing status of miR-3144-3pExpression levels of miR-3144 (research setting)

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