microRNA 3147 (miR-3147)

microRNA 3147 (miR-3147, MIR3147) is a small, non-coding RNA molecule classified as a microRNA[4]. MicroRNAs are involved in post-transcriptional regulation of gene expression, typically leading to mRNA degradation or translational repression[3]. miR-3147 has been described as an "oncomiR" in vulvar squamous cell carcinoma, acting via suppression of the tumor suppressor Smad4[4]. Its precise biological functions likely involve the regulation of gene networks controlling cell proliferation and tumorigenesis, but specific interacting drugs, use as a biomarker, or unique safety concerns have not been established in the available literature[4]. No evidence suggests that MIR3147 is a direct therapeutic target such as a receptor, enzyme, transporter, or similar; it is considered a regulatory non-coding RNA.

Other names

MIR3147hsa-mir-3147mir-3147