MicroRNA 3179-2 (MIR3179-2)

MicroRNA 3179-2 (MIR3179-2) is a human microRNA gene located in an intergenic region between the NOMO and PKD1P1 genes on chromosome 16, identified as possessing enhancer activity based on H3K27ac enrichment[1]. Experimental evidence suggests that miR-3179 (closely related to MIR3179-2) can upregulate neighboring genes such as ABCC6 and PKD1P1 in human cells, indicating enhancer-like functionality[1]. Like other microRNAs, MIR3179-2 is produced via canonical biogenesis involving Drosha and Dicer processing, and its mature form participates in post-transcriptional gene silencing through the RNA-induced silencing complex (RISC), typically modulating gene expression by targeting complementary mRNA sequences[2]. Specific biological roles, disease associations, or interactions with small-molecule drugs for MIR3179-2 are currently undefined in primary literature, reflecting its status as a noncoding regulatory RNA rather than a classical therapeutic target[1][2].

Other names

hsa-mir-3179-2MIR3179-2microRNA 3179-2