Target intelligence / Profile preview

MicroRNA 3180-2 (miR-3180-2)

Target
miR-3180-2
Molecular classification
MicroRNA (miRNA), Non-coding RNA, Small RNA
01

Overview

MicroRNA 3180-2 is a member of the human microRNA (miRNA) class, consisting of small (20–24 nucleotides) non-coding RNA molecules that mediate post-transcriptional regulation by promoting mRNA degradation or inhibiting translation through base-pairing with target mRNAs[3][4]. Like other miRNAs, MIR3180-2 is processed from a primary transcript (pri-miRNA) via Drosha and Dicer enzymes into its mature form, which is then incorporated into the RNA-induced silencing complex (RISC)[4]. It is predicted to regulate gene expression, but there are no published functional or disease associations specific to this miRNA. Although some closely related miRNAs (such as miR-3179 and miR-3180) are located in an intergenic cluster on chromosome 16 and have been studied for potential regulatory functions, there is no evidence that miR-3180-2 functions as an enhancer RNA or regulator in disease mechanisms[1]. If you need further specificity about the gene context or associated transcripts, note that MIR3180-2's functional characterization remains limited in major databases and the literature.

Other names
MIR3180-2hsa-mir-3180-2miR-3180-2
02

Biological functions

Post-transcriptional regulation of gene expressionModulation of mRNA stability and translationPotential involvement in enhancer-associated gene regulation (demonstrated for some related miRNAs)
03

Disease associations

Other (Some association for the related MIR3180-3 with Middle East Respiratory Syndrome, but no direct evidence for MIR3180-2)

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