Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
MicroRNA 3194 (MIR3194)
- Target
- MIR3194
- Molecular classification
- microRNA, Non-coding RNA, Small RNA (miRNA family)
01
Overview
MicroRNA 3194 (MIR3194) is a small non-coding RNA sequence expressed in humans and classified within the microRNA gene family. MicroRNAs function predominantly in post-transcriptional regulation by binding complementary messenger RNA, resulting in either translational inhibition or mRNA degradation. MIR3194 has been associated with endocrine gland cancer and is implicated in reproductive physiology, specifically in regulating aquaporin (AQP1, AQP9) and S100A9 protein expression to modulate trophoblast migration and invasion in the endometrium[1][3][4]. It is processed from longer pri-miRNA transcripts through the sequential action of Drosha and Dicer enzymes, generating mature forms incorporated into the RNA-induced silencing complex (RISC) for target recognition. MIR3194 and its variants (isomiRs) may exhibit functional diversity in different tissues or disease states, but it is not a primary receptor, enzyme, or transporter target for drugs[1][2][3][4].
- Other names
- MIR3194microRNA 3194hsa-mir-3194mir-3194
02
Biological functions
Post-transcriptional gene regulationmRNA destabilization or translational inhibitionMay modulate cell migration and invasion via targeting specific gene networks (e.g., regulation of AQP1, AQP9, S100A9)
03
Disease associations
Cancer (notably endocrine gland cancer and some evidence in lung non-small cell carcinoma)Reproductive biology: regulation of trophoblast migration and invasion (association with endometrial physiology)
04
Biomarkers
Potential biomarker roles in cancer (endocrine gland cancer) and reproductive status, based on expression profiles and isomiR diversity
Beyond the preview
Go deeper on MicroRNA 3194 (MIR3194).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on MicroRNA 3194 (MIR3194).