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Target intelligence / Profile preview
MicroRNA 3605 (MIR3605)
- Target
- MIR3605
- Molecular classification
- microRNA, non-coding RNA
01
Overview
MicroRNA 3605 is a small (20–24 nucleotides) non-coding RNA transcribed in humans, playing a role in gene expression regulation by binding to complementary sequences in messenger RNAs. It follows canonical miRNA biogenesis: transcribed by RNA polymerase II, processed by Drosha in the nucleus, further processed by Dicer in the cytoplasm, and incorporated into the RNA-induced silencing complex (RISC) for mRNA target recognition and regulation. MIR3605, like other miRNAs, may influence various cellular functions and be implicated in disease pathways, but there is limited direct biological or clinical evidence specific to MIR3605 beyond an association with cone-rod dystrophy 6.
- Other names
- hsa-mir-3605mir-3605MIR3605
02
Mechanism of action
RNA-induced silencing complex (RISC)–mediated inhibition or destabilization of target mRNAs
03
Biological functions
Post-transcriptional regulation of gene expressionControl of mRNA stability and translationPotential involvement in cellular processes regulated by miRNAs (such as cell differentiation, proliferation, apoptosis, etc.)
04
Disease associations
Cone-rod dystrophy 6 (reported association)Potential, but not established, roles in cancer and other diseases reflecting general properties of microRNAs
05
Safety considerations
None documented for MIR3605 specifically; RNA-targeted therapies may have off-target effects, immune responses, and delivery challenges as general concerns for miRNA-based therapies
06
Biomarkers
No specific validated biomarkers for patient selection or efficacy monitoring are reported for MIR3605; however, microRNAs in general can serve as biomarkers in cancer and other diseases
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