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Target intelligence / Profile preview
MicroRNA 3617 (miR-3617)
- Target
- miR-3617
- Molecular classification
- microRNA, Non-coding RNA, Regulatory RNA
01
Overview
MicroRNA 3617, abbreviated as miR-3617 (MIR3617; hsa-miR-3617), is a short, single-stranded, non-coding RNA (20–24 nucleotides) encoded in the human genome. Like other microRNAs, it regulates gene expression post-transcriptionally by base-pairing with target messenger RNAs, leading to mRNA destabilization or translational inhibition. MicroRNAs can participate in diverse biological processes such as cell differentiation, proliferation, apoptosis, and are increasingly studied for their roles in disease development and progression, including cancer and metabolic diseases. The specific gene regulatory targets and phenotypic effects of miR-3617 have not been thoroughly characterized in the available literature, but it is included in miRNome analyses of cancer and may target hundreds of downstream genes in certain contexts.
- Other names
- MIR3617hsa-miR-3617miR-3617hsa-mir-3617
02
Mechanism of action
Not applicable for direct drugs (miRNAs regulate gene silencing through pairing with mRNA, leading to mRNA destabilization, degradation, or translational repression)
03
Biological functions
Post-transcriptional regulation of gene expressionRNA silencingmRNA destabilization and degradationTranslational inhibitionInvolvement in cell differentiation, proliferation, and apoptosis as general microRNA functions
04
Disease associations
Potentially involved in cancer (general microRNA implication; specific evidence for miR-3617 not confirmed in search results but its altered expression was noted in breast cancer models)Other (miRNAs in general play roles in metabolic, cardiovascular, and developmental diseases)
05
Safety considerations
None specific to microRNA 3617 identified. General challenges with microRNA-targeted therapies include off-target effects and delivery issues.
06
Biomarkers
MicroRNAs as a class are investigated as biomarkers for disease diagnosis and monitoring, but no specific evidence for microRNA 3617 biomarkers is available in the provided results
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