Target intelligence / Profile preview

microRNA 4267 (MIR4267)

Target
MIR4267
Molecular classification
microRNA, non-coding RNA
01

Overview

microRNA 4267 (MIR4267) is a small non-coding RNA in humans (hsa-mir-4267), classified as a microRNA. It acts as a post-transcriptional regulator by binding to the 3' untranslated regions of target mRNAs, leading to gene silencing either by translational inhibition or mRNA degradation[1][2]. MIR4267 has been implicated in regulating pathways involving genes such as FOS and MAPK3 and may participate in processes related to glial cell development (gliogenesis)[2]. While it is upregulated in certain cancers (for example, it is co-expressed with other microRNAs during hepatocellular carcinoma development), its precise biological functions and disease associations remain incompletely established, and no direct clinical applications (such as drugs or biomarker use) have been validated[2][7]. Like other microRNAs, MIR4267 forms part of the complex gene regulatory network in mammalian cells[6]. If further structural or molecular detail is required, sequence information and predicted targets can be explored in dedicated RNA databases, but current experimental evidence for function and clinical role remains limited[2].

Other names
hsa-mir-4267MIR4267
02

Biological functions

Regulation of gene expressionPost-transcriptional gene silencingPotential involvement in gliogenesis (development of glial cells)
03

Disease associations

Cancer (appears co-expressed in hepatocellular carcinoma and may play a role in cancer progression)Other (implicated in broader gene regulatory processes; specific roles still largely uncharacterized)

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