MicroRNA-4306 (miR-4306)

MicroRNA-4306 (miR-4306) is a short non-coding RNA molecule that functions as a microRNA involved in post-transcriptional regulation of gene expression[1][2]. It acts primarily as a tumor suppressor in several cancers, including colorectal cancer and triple-negative breast cancer, where its downregulation is associated with increased malignant behaviors such as cell proliferation and tumor progression[1][2]. miR-4306 is known to be regulated by long non-coding RNAs such as FOXD2-AS1, which can act as a "sponge" for miR-4306, reducing its tumor-suppressive effects[1][2]. Overexpression or restoration of miR-4306 inhibits cancer cell proliferation, suggesting potential as a therapeutic target and as a biomarker for certain cancers[1][2]. There are currently no approved drugs specifically targeting miR-4306; ongoing research focuses on miRNA mimics or antisense molecules as potential therapies[1][2].

Other names

miR-4306MIR4306hsa-mir-4306mir-4306

Antisense inhibition of miR-4306 (potential therapeutic strategy), miRNA mimic therapy (experimental)