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Target intelligence / Profile preview
microRNA 4444-2 (MIR4444-2)
- Target
- MIR4444-2
- Molecular classification
- MicroRNA, Non-coding RNA
01
Overview
microRNA 4444-2 is a human non-coding RNA molecule from the microRNA family, implicated in post-transcriptional gene regulation. Elevated expression of miR-4444-2 is associated with poor prognosis in pancreatic adenocarcinoma, showing a correlation with increased proliferation and migration of pancreatic cancer cells. While miR-4444-2 has been used as part of a four-miRNA biomarker panel for risk stratification in pancreatic cancer, its precise molecular targets and broader functional roles remain to be experimentally validated. There is currently no evidence for direct therapeutic targeting or specific drug interactions with miR-4444-2[1][3][4].
- Other names
- hsa-mir-4444-2MIR4444-2miR-4444-2
02
Biological functions
Regulation of gene expressionPromotion of cell proliferation and migration in pancreatic cancer cells
03
Disease associations
Cancer (specifically implicated in pancreatic adenocarcinoma prognosis)
04
Biomarkers
Prognostic biomarker for pancreatic adenocarcinoma patient risk stratification
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