Target intelligence / Profile preview

microRNA 4479 (MIR4479)

Target
MIR4479
Molecular classification
microRNA, non-coding RNA, small RNA
01

Overview

microRNA 4479 (MIR4479) is a small, non-coding RNA molecule classified as a microRNA, a type of regulatory RNA involved in post-transcriptional gene silencing. Like other microRNAs, MIR4479 regulates gene expression by binding to complementary sequences on messenger RNA (mRNA), resulting in either translational repression or mRNA degradation[1][6]. It is found in exosomes circulating in plasma and has been identified as significantly downregulated in patients with epithelial ovarian cancer, suggesting its potential use as a diagnostic or prognostic biomarker for this malignancy[4]. Currently, there is limited functional characterization for MIR4479 beyond its biomarker role. There are no known drugs directly targeting MIR4479, and its specific molecular interactions and mechanisms in diseases remain to be elucidated. There is no evidence suggesting MIR4479 is a misspelled or invalid biological entity, but research describing detailed mechanisms or therapeutic targeting is still emerging. The primary literature identifies MIR4479 as a circulating biomarker for ovarian cancer, but does not detail functional roles, drug interactions, or disease mechanisms outside this context[4]. MIR4479 does not correspond to a receptor, enzyme, or transporter, but is a member of the microRNA family, a class of small non-coding regulatory RNAs[1][4][5]. No safety concerns or therapeutic challenges specific to MIR4479 are described. If additional studies emerge showing direct molecular mechanisms or therapeutic targeting, further details can be added. For now, MIR4479 is best documented as a non-coding RNA biomarker in ovarian cancer.

Other names
MIR4479hsa-mir-4479miR-4479
02

Biological functions

Regulation of gene expression (post-transcriptional)RNA silencingPotential role as circulating biomarker
03

Disease associations

Cancer (biomarker for epithelial ovarian cancer)Other (general roles in gene regulation; specific disease functions for miR-4479 are limited to biomarker status)
04

Biomarkers

Plasma exosomal miR-4479 (for epithelial ovarian cancer)

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