MicroRNA 4536-1 (MIR4536-1)

MicroRNA 4536-1 (MIR4536-1) is a human microRNA gene that produces a small, non-coding RNA transcript involved in post-transcriptional regulation of gene expression. Like other microRNAs, MIR4536-1 is processed from a primary transcript into a mature miRNA that incorporates into the RNA-induced silencing complex (RISC) to guide the silencing of specific mRNA targets, thereby regulating protein synthesis. MIR4536-1 has been implicated in the regulation of neuronal differentiation, influencing signaling pathways such as Wnt and MAPK. While microRNAs are broadly implicated in diseases including cancer and neurodegeneration, the specific disease associations and clinical relevance of MIR4536-1 require further research. MIR4536-1 is not a conventional pharmacological target (such as a receptor or enzyme), but may be considered an emerging target for oligonucleotide-based modulation in experimental settings.

Other names

hsa-mir-4536-1hsa-mir-4536MIR4536-1MIR4536microRNA 4536-1microRNA 4536

MicroRNAs downregulate target mRNAs via RNA-induced silencing, leading to mRNA degradation or translational repression. If therapeutically targeted, mechanisms would involve post-transcriptional gene silencing via RNA-induced silencing complex (RISC) or antisense inhibition.