MicroRNA 4648 (MIR4648)

MicroRNA 4648 (MIR4648) is a human microRNA gene encoding a small, single-stranded non-coding RNA molecule involved in post-transcriptional gene regulation[1]. Mature microRNAs, produced via Drosha and Dicer processing, are loaded into the RNA-induced silencing complex (RISC) and guide this complex to partially complementary mRNAs, resulting in translational repression or destabilization of target transcripts[1][2][4][7]. MicroRNAs, including MIR4648, play fundamental roles in cellular differentiation, development, metabolism, apoptosis, and tumorigenesis[2][5][6]. Alterations in microRNA levels are associated with diverse human diseases; MIR4648 is specifically associated with adamantinous craniopharyngioma according to current gene annotation[1]. MicroRNA mimics are used as research tools to study MIR4648 function in cells[3].\n\nFor future structured data retrieval, scientific databases like GeneCards, miRBase, and MedChemExpress can be referenced for up-to-date functional and genetic information regarding MIR4648[1][3].

Other names

hsa-mir-4648MIR4648microRNA 4648

For miRNA-targeting agents: gene silencing by mRNA degradation or translational inhibition. These mechanisms are typical, but no drugs for MIR4648 are listed.