MicroRNA 4667 (MIR4667)

MicroRNA 4667 (MIR4667) is a small, non-coding RNA gene in humans, belonging to the miRNA class of molecules. It is transcribed as a long primary transcript (pri-miRNA), processed by the Drosha and Dicer RNase III enzymes into a mature ~22 nucleotide miRNA. Like other miRNAs, MIR4667 functions as a post-transcriptional regulator by binding to partially complementary sequences in target mRNAs via the RNA-induced silencing complex (RISC), leading to translational inhibition or degradation of those mRNAs. MicroRNAs are deeply involved in the fine-tuning of gene expression and play key roles in development, immune responses, cell cycle regulation, and disease states. Specifically, MIR4667 is associated with juvenile ankylosing spondylitis, suggesting a possible role in immune-mediated processes. While MIR4667 itself does not currently have documented direct drug interactors or established mechanisms of clinical targeting, the miRNA family as a whole is under investigation as both biomarker and therapeutic target class in various diseases[1][2][3].

Other names

hsa-mir-4667mir-4667MIR4667