MicroRNA-4709 (miR-4709)

MicroRNA-4709 (miR-4709), also known as hsa-miR-4709, is a small non-coding RNA molecule that regulates gene expression post-transcriptionally. It functions primarily by binding to the 3′ untranslated regions of target mRNAs, leading to mRNA degradation or translation inhibition. miR-4709-3p, the active mature strand, has been implicated in the regulation of renal fibrosis, particularly through targeting Large Tumor Suppressor Kinase 2 (LATS2) and modulating the Hippo signaling pathway. Aberrant expression of miR-4709-3p is associated with progression of renal fibrosis and chronic kidney disease. It is considered a potential biomarker for fibrotic kidney diseases and presents a putative therapeutic target for intervention in fibrotic processes[2][1].

Other names

hsa-miR-4709MIR4709hsa-mir-4709mir-4709

Not applicable; small RNAs like miR-4709 are currently not directly targeted by approved drugs, but are considered potential gene therapy or RNA interference targets[2].