microRNA 4746 (MIR4746)

microRNA 4746 (MIR4746) is a small, non-coding RNA molecule involved in post-transcriptional gene regulation. It is differentially expressed in a variety of cancers and targets multiple genes, including PPM1D, contributing to processes such as cell proliferation, intracellular organization, tissue morphology, and immune responses. Its expression profile makes it a candidate for biomarker development and a novel therapeutic target in oncology. No direct drug interactions have been identified to date, but it is amenable to experimental manipulation by miRNA-based therapies

Other names

hsa-mir-4746mir-4746hsa-mir-4746-5pMIR4746

Therapeutic interventions targeting MIR4746, such as miRNA mimics or inhibitors, would modulate its post-transcriptional gene regulation activity. Mimics would enhance MIR4746's binding to complementary mRNA sequences (e.g., PPM1D) to induce degradation or translational inhibition, thereby altering cellular processes like cell proliferation. Inhibitors or antisense oligonucleotides would reduce MIR4746's activity.