Target intelligence / Profile preview

MicroRNA 4761 (MIR4761)

Target
MIR4761
Molecular classification
MicroRNA, Small non-coding RNA, RNA gene
01

Overview

MicroRNA 4761 (MIR4761) is a short (20–24 nucleotide) non-coding RNA encoded by the MIR4761 gene in humans. It functions in post-transcriptional regulation by interacting with messenger RNAs (mRNAs) to inhibit their translation or destabilize them, thus influencing gene expression. MIR4761 is processed from a primary transcript, undergoes maturation via Drosha and Dicer enzymes, and is incorporated into the RNA-induced silencing complex (RISC), which mediates its gene regulatory effects. The biological functions and disease roles of MIR4761 are currently not well characterized, and it is not considered a classical therapeutic target or biomarker.

Other names
hsa-mir-4761miR-4761
02

Mechanism of action

Not applicable. While miRNAs may be indirectly modulated by therapeutics (e.g., through epigenetic drugs or oligonucleotide-based therapies), there is no mechanism of drug action targeting MIR4761 directly described.

03

Biological functions

Post-transcriptional regulation of gene expressionmRNA stability and translation modulation
04

Disease associations

Some databases associate MIR4761 with Velocardiofacial Syndrome and Tic Disorder, but roles in other diseases remain poorly characterized. There is currently no evidence for a major direct role in widely studied diseases such20 as cancer, inflammation, cardiovascular disease, or infection.

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