microRNA 500a (miR-500a)

MicroRNA 500a (miR-500a) is a small, non-coding RNA molecule that functions as a post-transcriptional regulator of gene expression by binding to complementary sequences in target messenger RNAs. miR-500a exists in both -5p and -3p mature forms, and its expression has been implicated in several biological processes and diseases. In particular, miR-500a-5p modulates oxidative stress response genes and is upregulated in some breast cancer cell lines, especially those that are estrogen receptor positive. It influences the progression of breast cancer and may serve as a prognostic biomarker in this context. Like other microRNAs, miR-500a does not encode proteins but exerts its activity primarily through sequence-specific interaction with mRNA targets, leading to their degradation or translational repression[1][4].

Other names

hsa-miR-500aMIR500Ahsa-mir-500MIR500MIRN500hsa-mir-500amir-500amicroRNA 500

Not directly applicable, as microRNAs generally function by binding to complementary sequences in target mRNAs and causing their degradation or inhibition of translation