MicroRNA 548f-4 (MIR548F4)

MicroRNA 548f-4 is a short, non-coding RNA (typically 20–24 nucleotides) processed from a stem-loop precursor transcribed from the MIR548F4 gene[1][3]. This microRNA modulates gene expression by binding to complementary sequences on target messenger RNAs, leading to their translational inhibition or destabilization. Recent bioinformatics and expression studies have implicated members of the miR-548 family, including MIR548F4, in pathways relevant to cell cycle regulation, mitotic spindle assembly, and cancer—particularly triple-negative breast cancer—highlighting its potential as a prognostic biomarker and therapeutic target[2]. No established drugs currently act directly on MIR548F4, but its pivotal place in gene regulation and disease pathogenesis makes it a subject of ongoing research.

Other names

hsa-mir-548f-4MIR548F-4MIRN548F4MIR548F4

Drugs that might someday target this miRNA would likely inhibit or mimic its function to modulate target gene repression, but none are currently in use[2].