Target intelligence / Profile preview

MicroRNA 5682 (miR-5682)

Target
miR-5682
Molecular classification
MicroRNA (miRNA), Non-coding RNA, Other
01

Overview

MicroRNA 5682 is a non-coding RNA molecule classified as a microRNA (miRNA) that regulates gene expression post-transcriptionally through base-pairing with target messenger RNAs, leading to translational repression or mRNA degradation[2][4]. miR-5682 has been implicated in the regulation of genes associated with protein digestion and absorption, and it affects major signaling pathways such as the IGF1-Akt and PI3K-Akt, as well as inflammatory responses[1]. Elevated miR-5682 levels have been linked to poor nutritional status and worse survival in patients with laryngeal cancer undergoing radiotherapy, suggesting a potential role as a prognostic biomarker in oncology settings[1]. There is currently no evidence that miR-5682 is a direct therapeutic target or that there are specific drugs that interact with this miRNA.

Other names
hsa-mir-5682MIR5682
02

Mechanism of action

Functions via RNA interference to repress translation or degrade target mRNAs after binding complementary sites, primarily in the 3′ UTR of messenger RNAs. Downregulation of specific genes involved in protein metabolism (e.g., ESL and COL gene families).

03

Biological functions

Regulation of gene expression at the post-transcriptional levelModulation of protein digestion and absorptionInvolvement in insulin-like growth factor (IGF1)-Akt signalingRole in PI3K-Akt signaling and inflammatory response pathways
04

Disease associations

Associated with nutritional deficiencies and cancer cachexiaPrognostic in head and neck cancers, particularly laryngeal cancer
05

Biomarkers

High miR-5682 plasma expression as biomarker for poor nutritional status and reduced survival in laryngeal cancer patients during radiotherapy

Beyond the preview

Go deeper on MicroRNA 5682 (miR-5682).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Full profile access

Explore the programs pursuing this target and their development progress.

  • Drug candidates
  • Developers
  • Development stage

Clinical trials

Full profile access

Follow the clinical studies evaluating therapies directed at this target.

  • Trial design
  • Status
  • Readouts

Competitive landscape

Full profile access

Compare approaches across drug candidates, modalities, and indications.

  • Programs
  • Modalities
  • Indications

Literature & evidence

Full profile access

Investigate the research and source evidence behind target biology and development.

  • Publications
  • Sources
  • Analysis

Patents

Full profile access

Explore patent activity around therapies and technologies addressing this target.

  • Patents
  • Assignees
  • Technologies

Research & analysis

Full profile access

Connect target biology, drug development, and emerging evidence in your research.

  • Biology
  • Development news
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on MicroRNA 5682 (miR-5682).

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call