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microRNA 5698 (miR-5698) is a member of the human microRNA family, encoding a short non-coding RNA that primarily regulates gene expression at the post-transcriptional level via the RNA-induced silencing complex (RISC)[4]. It has been identified as a key component of the miRNA-mRNA regulatory network in lung adenocarcinoma, where it controls several hub genes involved in immune cell adhesion and cytotoxicity, tumor cell proliferation, and cell death[1]. miR-5698 is considered a promising biomarker for cancer prognosis and may inform future therapeutic strategies, either as a direct target or in monitoring response to treatment (for example, in metastatic breast cancer)[1]. Like other microRNAs, its broader functional role includes facilitating the finely tuned regulation of transcriptome dynamics, with implications in cell proliferation, immune responses, and apoptosis[3][4][6].
Not directly targeted by drugs yet; acts through the RNA-induced silencing complex (RISC) to regulate gene expression. Its modulation impacts oncogene and tumor suppressor pathways by targeting mRNAs involved in immune cell adhesion, cytotoxicity, and tumor proliferation.
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