MicroRNA 635 (miR-635)

MicroRNA 635 (miR-635) is a short non-coding RNA molecule (miRNA) that functions primarily in the post-transcriptional regulation of gene expression, typically by inducing mRNA degradation or translational repression through partial base pairing with target mRNAs[3][5]. It is processed from a stem-loop precursor and incorporated into the RNA-induced silencing complex (RISC), which guides it to its molecular targets[3][5]. miR-635 acts as a tumor suppressor in various cancers, notably inhibiting cell invasion and xenograft tumor growth in non-small cell lung cancer and showing differential expression in normal versus cancerous tissues[1][3]. It also targets transcription factors such as Ying Yang 1 (YY1), thereby influencing cell proliferation, invasion, and other cancer-associated behaviors[1][3]. Diseases associated with MIR635 include ovarian cancer and potentially other malignancies, but as of now, there are no specific drugs known to interact directly with miR-635, nor is it classified as a therapeutic target like a classic receptor, enzyme, or transporter[3].

Other names

hsa-mir-635MIRN635MIR635