Target intelligence / Profile preview

microRNA 6746 (MIR6746)

Target
MIR6746
Molecular classification
microRNA (miRNA), Non-coding RNA, Other (extracellular RNA biomarker)
01

Overview

microRNA 6746 (MIR6746) is a small non-coding RNA that functions in post-transcriptional regulation of target genes. It is found extracellularly and can be detected in plasma, where its elevated expression is specifically associated with pancreatic cancer relative to other cancer types and healthy controls. MIR6746 serves as a computationally validated signature for cancer classification and is recognized as a promising biomarker for early diagnosis, patient monitoring, and potentially for future functional studies in tumorigenesis. No direct interactions with drugs have been reported for this microRNA at present, and its therapeutic targeting, while theoretically possible via RNA-based therapeutics, remains unproven in clinical settings.

Other names
hsa-miR-6746microRNA mir-6746hsa-mir-6746
02

Biological functions

Post-transcriptional gene regulationCancer subtype biomarker
03

Disease associations

Cancer (most notably pancreatic cancer, specificity as circulating biomarker)
04

Biomarkers

Circulating extracellular RNA biomarker for pancreatic cancer diagnosis and monitoring

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