microRNA 7111 (miR-7111)

microRNA 7111 (miR-7111, hsa-miR-7111) is a small, endogenous non-coding RNA molecule that regulates gene expression post-transcriptionally by binding to target mRNAs and inhibiting their translation or promoting their degradation[3]. It is implicated in the regulation of genes involved in metabolic, biosynthetic, cell cycle, and stress response processes[2]. Dysregulation of miR-7111, especially the 5p strand (miR-7111-5p), has been associated with certain cancers such as colorectal cancer and hepatocellular carcinoma, often through modulation of apoptosis-related genes such as BAK1[1][2]. Its role as a gene regulator in cancer highlights its emerging investigative importance as both a biomarker and a potential therapeutic target, although direct therapeutic strategies targeting miR-7111 are not yet established. If detailed drug interactions or mechanisms of action for drugs specifically targeting miR-7111 are required, further research and updated literature searching is necessary as current reports focus primarily on its biological and disease relevance.

Other names

hsa-miR-7111-5pMIR7111microRNA mir-7111hsa-mir-7111

miR-7111 exerts its effect via post-transcriptional repression of target genes, such as BCL2-antagonist/killer 1 (BAK1). In cancer, by downregulating pro-apoptotic genes such as BAK1, miR-7111-5p may induce tumorigenesis.