Target intelligence / Profile preview

MicroRNA 7114 (MIR7114)

Target
MIR7114
Molecular classification
MicroRNA, Non-coding RNA
01

Overview

MicroRNA 7114 (MIR7114) is a small non-coding RNA molecule classified as a microRNA that regulates gene expression post-transcriptionally, typically by binding to target mRNA and inhibiting translation or promoting degradation. MIR7114 has been studied in the context of colorectal cancer, where it shows an inverse expression correlation with the CEACAM1 gene, suggesting a role in early tumorigenesis and potential usefulness as a molecular biomarker for colorectal cancer[1][6]. There is currently no evidence that MIR7114 itself acts as a direct therapeutic target, nor are there known drugs or clinical interventions that specifically modulate its activity. Its function and disease associations require further study for therapeutic targeting.

Other names
hsa-mir-7114miRNA-7114microRNA mir-7114MIR7114
02

Mechanism of action

Not applicable (no drugs known to directly target MIR7114)

03

Biological functions

Post-transcriptional regulation of gene expressionRNA silencing
04

Disease associations

Colorectal cancer (early development, potential molecular marker)Other (potentially, but not well-established)
05

Safety considerations

None reported (microRNAs are not direct therapeutic targets; delivery/inhibition of miRNA in therapy can have off-target effects, but nothing specific to MIR7114 is reported)
06

Biomarkers

Potential biomarker for early colorectal cancer (based on inverse correlation with CEACAM1 expression)

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