Target intelligence / Profile preview

MicroRNA 877 (MIR877)

Target: MIR877
Molecular classification: microRNA, Non-coding RNA, Regulatory RNA

Overview

MicroRNA 877 (MIR877) is a short, non-coding RNA classified as a microRNA (miRNA). It functions primarily in post-transcriptional regulation of gene expression by binding to target messenger RNAs (mRNAs), affecting their stability and translational efficiency. MIR877 is involved in several biological processes and may play a dual role as either an oncogene or tumor suppressor, depending on cellular context. It has been implicated in the development of various diseases, notably several cancers (such as gastric and prostate cancer), as well as cervix and bladder diseases

Other names: hsa-mir-877MIRN877miRNA877mir-877MIR877

Biological functions

Post-transcriptional regulation of gene expressionmRNA stability and translation inhibitionTumor suppressionOncogene activity (context-dependent)

Disease associations

Cancer (oncogene in gastric cancer, tumor suppressor in prostate cancer)Cervix diseaseBladder disease

Safety considerations

Potential for context-dependent oncogenic or tumor-suppressor roles (therapeutic targeting may risk unintended effects in non-target tissues)

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