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Microtubule-associated protein 1 light chain 3 beta 2 pseudogene (None established; this entity is often referenced by its locus ID (LOC107984761) or Ensembl gene ID (ENSG00000259392), but there is no canonical abbreviation in regular use.)
- Target
- None established; this entity is often referenced by its locus ID (LOC107984761) or Ensembl gene ID (ENSG00000259392), but there is no canonical abbreviation in regular use.
- Molecular classification
- Pseudogene, Other
01
Overview
Microtubule-associated protein 1 light chain 3 beta 2 pseudogene (LOC107984761, ENSG00000259392) is annotated as a pseudogene, specifically related to the protein-coding gene MAP1LC3B, which encodes a key autophagy-related protein (LC3B) involved in formation of autophagosomes[2]. However, the pseudogene itself (MAP1LC3B2P, LOC107984761) is not expressed as a functional protein and does not have known biological function, disease linkage, or relevance as a drug target. Pseudogenes typically arise from duplication or retrotransposition of functional genes, followed by loss of protein-coding ability. As such, this locus should not be considered a bona fide therapeutic or biological target. The canonical, functionally relevant gene regarding microtubule-associated protein 1 light chain 3 beta is MAP1LC3B (not this pseudogene)[4][2]. For structured curation, this entry should be marked as incorrect or not a target.
- Other names
- LOC107984761MAP1LC3B2PMAP1LC3B pseudogene 2
02
Mechanism of action
None
03
Biological functions
None (no direct protein-coding function; pseudogenes are, by definition, non-functional in the classical protein-coding sense)
04
Disease associations
None directly documented; as a pseudogene, there is no established role in disease
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